Research areas: Biotherapeutics & Neurodegenerative Disease models
About: 7 years of research experience including development of sophisticated
surgical skills in rodents i.e. stereotaxic surgery, pterygopalantine
artery occlusion and sub-retinal/Intravitreal/Intravenous delivery for
validating therapies in Neurodegenerative diseases. For this I
used established molecular and statistical tools such as real time PCR,
Neurobehavioural assays, immunohistochemistry, nucleic acid
extraction, confocal imaging, SPSS, FACS and in-vitro systems.
My research interest includes investigation of molecular pathways
underlying neuronal development and neurodegenerative disorders.
In my doctoral thesis, we showed that CD34 and CD117 stemness in
lineage negative stem cells reverses memory loss induced by amyloid
β in the mouse model of memory loss (Front. in Behav Neurosci.
2018). Further analysis indicated the role of neurotrophic factors in
the activation of astrocytes, possibly ameliorating memory loss by
amyloid clearance (Mol Neurobiol 2019, Patent ID:201911038513). My
work also led me to examine the comparative efficacy of human ciliary
epithelium cells from fetal eyes and Lin-ve stem cells from umbilical
cord blood (Cell Transplant 2020) in laser injury mouse model for
I provided frontline assistance in voluntary operationalization of Good
laboratory practice, eventually resulting in my former lab becoming
India’s first QCI awarded research laboratory (Int J Sci Res 2019). I
have also been mentored in several academic social activities to
enable me to work in large teams.
My academic goal is to utilize above skills for translational research in